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Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases
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Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases
Source
nature.com
Type
Technical article
Language
English
Published on
December 04, 2023
BMP-1/tolloid-like proteinases (BTPs) are major players in tissue morphogenesis, growth and repair. They act by promoting the deposition of structural extracellular matrix proteins and by controlling the activity of matricellular proteins and TGF-β superfamily growth factors.